Pyridine

Pyridine is a colorless liquid with a foul odor and several hazardous properties.Pyridine (C5H5N) is being the simplest six-membered heterocycles, closely resembles its structure to benzene. The “N” in benzene ring has its high electronegativity influence on resonance environment and produces markedly different chemistry from its carbon analog. The presence of nitrogen and its lone pair in an aromatic environment makes pyridine a unique substance in chemistry. The sp2 lone pair orbital of “N,” directed outward the ring skeleton, is well directed to have overlap with vacant metal orbital in producing an σ bonding interaction. This causes pyridine to be a ligand and has been utilized with all transition metals in producing the array of metal complexes.

Application
Pyridine may be used as a base for the conversion of:
Alkyltrichlorosilanes to trimethoxyalkylsilanes, which are used as precursors for preparing alkylsilicates.
1-Indanone to 1-indanone oxime, which can undergo reductive ring-expansion to form tetrahydroquinoline.

It may also be used to catalyze the borylation reaction of haloarenes to form arylboronates without using transition metal catalysts.
Pyridine (py) may be used in the preparation of vanadium oxide nanoparticles and iron benzenedicarboxylates, Fe(OH)(BDC)(py)0.85 (BDC = 1,4-benzenedicarboxylate, py = pyridine). It may be employed as catalyst in Knoevenagel condensation reaction.

Products

Pyridines

Pyridine